Posted by Gup on April 22, 2011, at 16:49:50
In reply to Pseudoephedrine (sudafed), posted by blueboy on April 9, 2010, at 9:52:55
> I got hay fever and took some Sudafed (2x30mg pseudoephedrine). The results were miraculous. My only side effects are insomnia, which is actually not as bad as it was on Mirapex at higher dosage; mild hypomania; and weight loss!
I discovered a similar effect, and found this thread while trying to research just exactly what was going on. I have unipolar major depression, and discovered that 1x 120mg time-release Pseudoephedrine gave me a substantial boost in mood and focus, as well as reduction in anxiety (which I did not expect from a sympathomimetic such as pseudoephedrine).
I've tried skipping a few days at a time, and there is definitely a difference when I take it. While it is possible a placebo effect is in play, I have failed trials on many other anti-depressants, and the effect of the pseudoephedrine is pretty dramatic.
After playing around with dosage time a bit, I now take it at night just before bedtime (doesn't seem to disrupt my sleep, and it's possible I may be sleeping better, actually).
Thus far, I only have a few weeks of experience with PE. I'm not sure if the best tactic will be to occasionally skip doses (if it builds tolerance), or to take it daily (if it works best with consistent use, like many anti-depressants).
Blueboy, if you happen to see this post -- any chance you'd be willing to point me in the direction of the Emory researchers? I would be interested to know if they have any information on what may be going on (or to offer any information that could further their research).
poster:Gup
thread:942830
URL: http://www.dr-bob.org/babble/20110418/msgs/983532.html