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Re: Pseudoephedrine (sudafed)

Posted by desolationrower on May 3, 2011, at 21:09:51

In reply to Re: Pseudoephedrine (sudafed), posted by Gup on May 3, 2011, at 18:24:47

> Ok, thanks for the update. Any opinion on Protriptyline as well? I see it's listed as causing more psychomotor stimulation than other TCAs.
>
>

Its hard to get information on it (nothing on the kidb, but TCA page on wiki does have values), but if i recall correctly it works similarly as other secondary amine tcas (i would geuess more stimulation is a combination of less sedation from the mach, antihist, sri, etc effects that tcas like imipramine or amytryptaline have, plus you can/need to push the nri harder to get full depression relief.) It is not one of the genotoxic TCAs (http://www.ncbi.nlm.nih.gov/pubmed/1902910), so i guess that might be a reason to choose it vs desipramine.

-d/r


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URL: http://www.dr-bob.org/babble/20110502/msgs/984473.html