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Re: Going back to old-school - lithium. » floatingbridge

Posted by SLS on January 25, 2010, at 19:38:39

In reply to Re: Going back to old-school - lithium. » SLS, posted by floatingbridge on January 23, 2010, at 14:22:13

Hi FB.

> Hi Scott, after rereading this thread, I had a few thoughts. At thanksgiving, you had baseline improvement at about 40%. What is the current estimate?

20% - 25%

> I forget when you began the effexor--how is it? Probably too early to judge.

Probably. A few days ago, I experienced a significant improvement that lasted for about a day. Nothing since. If things follow my usual pattern of response, that brief improvement is all I can expect.

> I don't see any stimulant on board (except for effexor--is that enough?)--any
> reason for that?

I just started taking Adderall today.

> Off of parnate, would segeline add some neuroprotection in addition to low-dose lithium?

I experienced an irritable type of dysphoria with Emsam. I stopped taking it after 3 or 4 days.

> Miraprex or another dopamergenic (is that a word?). Would you consider this type of add-on?

I haven't tried Mirapex yet. I tried bromocriptine (Parlodel) a long time ago, but it did very little to improve my depression.

> To me, the history of this thread doesn't seem to indicate a great threat of inducing mania, except as you've noted,
> and cycling. So you used to be ultra-rapid or somewhat 'disorganized'?

I exhibited a dramatic mood-swing between depression and euthymia that followed a regular cycle of 11 days. I would spend 8 days depressed followed by 3 days of euthymia. The switch between one state and the other took about 45 minutes.

> What are your current doses? Ricker has suggested less lamictal. I don't know....

I tried going lower on Lamictal, but I began to deteriorate. 200mg seems to be the minimal effective dosage for me.

Right now, I'm taking:

Effexor 300mg
nortriptyline 150mg
Lamictal 200mg
Abilify 10mg
lithium 300mg
Adderall 20-40mg

> Wondering if the pharmaceutical lid is
> too heavy. Dopamine? Maybe abilify isn't quite right.

Someone here suggested that I give Zyprexa a try. I have been on it in the past. It would help for the better part of the first week, then nothing. I haven't tried it in combination with my current medications, though.

> Hope today is a decent one,

I survived it without incurring too many bruises. It was a decent day.

:-)


- Scott

 

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