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Re: to all of you » Jeroen

Posted by yxibow on July 20, 2009, at 2:52:29

In reply to to all of you, posted by Jeroen on July 19, 2009, at 19:49:53

> nothing is going on im still an inpatient, but im affrai to take Sertindole because i might have cardiac disease

As I noted, Mellaril is much more likely to cause QTc elongation.

Nevertheless, I also said that Sertindole was not approved in the US eventually because it does have some risk of QTc elongation greater than those in its class.

Geodon also has QTc elongation risk, but was approved here because the chance was reexamined to be less than 1/4000.


Yes, when faced with a choice of a medication it is always a choice whether the benefits will outweigh the risks.


Is there any heart disease or defects in your family ? Have you ever had a heart murmur?

An EKG should be performed before starting the agent. It should also probably be used periodically (not obsessively... in terms of months perhaps) to check on how it works.


But it all comes down to this... and don't think I'm trying to be mean....


I know you've been struggling with things for a long time....

but with an antipsychotic, even if in some people there is a noticeable difference in as little as a few weeks, it takes several months to really notice a difference...

I'm concerned that fears may have led to stopping medications before they had a chance to work. Yes, I know that Clozaril made you extremely lethargic and had some bad effects --- this is common in a lot of patients.

The question is... which one to keep an open mind on, at least for a month or two.

Now I'm not asking you to endure undue harm or a terrible situation, that would be Schadenfreude... but give things a reasonable chance.


-- good luck


-- tidings

Jay

 

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