Posted by SLS on July 18, 2009, at 6:04:49
In reply to to Zyprexa, posted by Jeroen on July 18, 2009, at 4:57:55
> abilify is not powerfull enough for an induced psychosis
True. When Abilify is added to Clozapine for example, it does not reduce positive symptoms, although it does help with negative symptoms.
I can't be sure, but Abilify might even reduce the effectiveness of other antipsychotics in some circumstances. If you decide to go back to Seroquel, I'm hoping that it works better for you at a reduced dosage. Abilify acts as a partial D2 and D3 receptor agonist and has greater binding affinity than Seroquel. The Seroquel is probably not blocking as many receptors. One woman I know of had a wonderful response to Risperdal 3.0mg combined with Seroquel 200mg. When the Risperdal was substituted for with Abilify, she needed to raise the Seroquel to 800mg.
Since your doctors were willing to use polypharmacy by combining Abilify with a series of different antipsychotics, why would they be unwilling to leave Seroquel in place and try using other drugs to augment it?
- Scott
poster:SLS
thread:907243
URL: http://www.dr-bob.org/babble/20090709/msgs/907314.html