Posted by desolationrower on May 13, 2009, at 10:11:10
In reply to Tryciclics SSRIs and MAOIs + receptors, posted by meltingpot on May 11, 2009, at 15:07:29
> Hi,
>
> Well I'm still taking this clomipramine, anxiety is not so bad but I'm just dragging myself around from day to day. Constantly fatigued, inspite of getting 10 hours sleep a night.
>
> My question is this. I would be prepared to suffer this out for a year on Clomipramine if I thought that by staying off Seroxat for a year then it might actually work again if I go back on it for a year.
>
> I tried coming off Seroxat for about 2 months and going back on it and it still didn't work so not sure if staying off it a year would make any difference.
>
> I'm not sure why the Seroxat stopped working after two years, either my depression has just got worst and I've become more resistant than ever or somehow seroxat did something that had an adverse affect after a period of time which maybe could be undone after a period of time.
>
> I'm just clutching at straws again, does anyone have any ideas on this?
>
>
> Thanks......DeniseHi, sounds like you are out of hope :(
I wonder if taking a drug that is an snri is going to keep you from having 5ht receptors 'reset'...the only thing i can think of would be either inositol or tianeptine or SAMe, its possible they might 'reset' things (and be helpful now too) since they all 'improve' 5htergic function in one way or another, although i don't have any evidence really they reset things (and its more likely they'd work now, than that they'd not work but make seroxat work 6mo from now, i think).
-d/r
poster:desolationrower
thread:895198
URL: http://www.dr-bob.org/babble/20090505/msgs/895519.html