Posted by SLS on May 1, 2009, at 18:01:39
While eating my Raisin Bran earlier, it occurred to me that in OCD there is probably something out of whack in the balance between the locus coeruleus and raphe nuclei - the regional source of norepinephrine (NE) and serotonin (5-HT) respectively. Perhaps this is why clomipramine works so well. It might help to reregulate both pathways simultaneously.
Why not combine Prozac, an atypical SSRI with anti-OCD properties, with either desipramine or nortriptyline to treat OCD and avoid the anticholinergic side effects of clomipramine?
Just a thought.
- Scott
poster:SLS
thread:893777
URL: http://www.dr-bob.org/babble/20090426/msgs/893777.html