Posted by desolationrower on December 6, 2008, at 15:43:14
In reply to Stimulants to Improve Sleep in Adults with ADD, posted by Jakeo29 on December 6, 2008, at 12:26:36
might want to look up
Neurology. 2004 Oct 26;63(8 Suppl 3):S2-7.Click here to read Links
The two faces of Eve: dopamine's modulation of wakefulness and sleep.
Rye DB.In Parkinson's disease (PD), waking is frequently punctuated by sleep episodes, including rapid eye movement (REM) (i.e., dream) sleep, and sleep is interrupted by motor activities such as periodic limb movements and REM sleep behavior disorder. Because these pathologic behaviors are unaccounted for by contemporary models, this review summarizes the complex effects of dopamine (DA) on normal and pathological waking-sleeping. Maintenance of wakefulness is probably promoted by mesocorticolimbic DA circuits, and suppression of nocturnal movement appears to be influenced by indirect pathways linking midbrain DA neurons with pre-motor structures in the mesopontine tegmentum and ventromedial medulla. A diencephalospinal DA system may have an additional important role in mediating state-specific sensorimotor activity that is relevant to periodic limb movements and restless legs syndrome.
-d/r
poster:desolationrower
thread:867016
URL: http://www.dr-bob.org/babble/20081204/msgs/867064.html