Posted by uncouth on November 2, 2008, at 9:53:33
In reply to MAOIs, and PDoc Rant » JadeKelly, posted by Questionmark on October 31, 2008, at 17:31:41
just want to make clear that my pdoc didn't start me on nardil at 90mg within two weeks. i believe i started at 30 and went up to 60 for a few weeks before going to 90 for 1.5 weeks.
i do think the switchover was potentially not the best idea in terms of side effects, but i'm guessing i gave up on nardil probably just as it was kicking in, because when i went to parnate, i felt the response within a day or two. i likely was probably getting near 100% MAO inhibition for a while due to the high dose of nardil, then switching to parnate, and over time, the lower equivalent dose of parnate (40mg equates to 60mg of nardil) likely caused teh % inhibition to actually go down, so side effects went away, but mood also wasn't as great as it was when the side effects were in full force.
i'm planning on going back up to 60mg of parnate which equates to 90mg of nardil, so hopefully this time i'll get the mood benefits without the major side effects.
nardil would have been fine long term, except for the terrible side effects. i'm happy with parnate, it feels much better than emsam did. emsam was far too speedy and anxiety inducing, but who knows perhaps if parnate ever poops out i'd consider emsam again, this time with some abilify to help with the anxiety.
all i know is, these MAOIs are great. i feel closer to well than i ever have, and feel like the only thing that's left int erms of mood and behavior and life are things that can be done with psychotherapy and behavioral changes. rejection sensitivity is still pretty bad, but i'm guessing that's more of a learned behavior from years of depression, and i'm hoping that now that i'm on a solid a/d regime, i won't be as sensitive to rejection. at least that's the theory.
compared to effexor and cymbalta, parnate and the MAOIs have given me far more self control, they have helped attention and motivation an anhedonia, they haven't exacerbated cravings for alcohol and carbs and obsessively using the internet like effexor did. it's a shame more doctor's don't prescribe MAOIs, and parnate and nardil should really come in a patch form too, as i think they are superior meds to selegiline.
all i know is i never ever want to go back on an SSRI. i have bp2 tendencies and while I felt great on effexor for a few weeks, the compulsiveness and acting without thinking and feeling of bliss seemed extremely artificial. the MAOIs feel much more natural, and ironically although parnate has some stimulant properties, in terms of speed and expansiveness of thought, is far less 'speedy' in that sense than effexor was.
i just wish i could sleep well :(
and wasn't so hungry. parnate (or abilify, i dont know which) makes me hungry.anyway, hope this helps. i decided not to do the selegiline thing. probably too dangerous. maybe will try a tiny dose every few days for neuroprotection and antioxidant benefits. seems like even 1mg daily can work, and at that dose i won't likely feel anything.
-uncouth
poster:uncouth
thread:858948
URL: http://www.dr-bob.org/babble/20081027/msgs/860351.html