Posted by JadeKelly on October 31, 2008, at 0:24:39
In reply to Re: MAOI Experts: Combining Parnate with Selegiline » uncouth, posted by Questionmark on October 30, 2008, at 15:53:51
Just a bad idea at any dose, imo. One MAOI seems risky enough, mixing 2 which is a big no-no? I was on the emsam patch, no problems. Switched to Parnate, it works but I doubt it should be played with.
I'm not an expert, but I was great on Parnate (alone) for 11 days, full response. 11th day bad hypertensive crisis out of nowhere. I'm anal about the food/drug restricts. I, too, had low BP until "the spike".
After that, went back on assuming it was random food mistake. I had BP up to 190 after every dose.
I took 30mg in morn. When I split them, spike after 3rd dose.My point is, Parnate isnt a drug to mess around with. I read somewhere that not only could small amount of amphetimine cause HT crisis, but also bleeding in the skull. Ouch. Even just the mix of 2 MAOI's could cause HT crisis. I can tell you likely havent had one...scary and dangerous.
If you do this, please do it with close supervision, get antidote ready, and get BP cuff. Now I take nifedipine before my 30mg dose, and no more spikes. Not sure I can stay on it more than 10 days. Up to pdoc as I don't know anything about the antidotes out there. I'd hate to give Parnate up but may have to.
Be careful and good luck. Post re: your decision, and results if you go with it!
Jade
poster:JadeKelly
thread:858948
URL: http://www.dr-bob.org/babble/20081027/msgs/860020.html