Posted by undopaminergic on June 5, 2008, at 16:16:27
In reply to Re: Mirapex vs. Seroquel for SSRI-induced anhedoni, posted by linkadge on May 30, 2008, at 16:32:11
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> For SSRI anhedonia, I would not really recomend an AP at all. They can augment SSRI's for depression, but I don't think there is much research showing they improve anhedonia.
>While they may not do much for anhedonia, low doses of sulpiride and amisulpride can have powerful effects against apathy, quite possibly including SSRI-induced apathy. Sulpiride was a more powerful stimulant than methylphenidate for me until its effects dissipated, and its side-effects were non-existent.
Aripiprazole (Abilify) is another antipsychotic that may be stimulating and effective against apathy, but some people experience the opposite.
Pimozide is a stimulating antipsychotic as well, but it's not as safe as the agents mentioned above, so its use requires more caution.
Most other antipsychotics - especially the atypicals - are likely to be sedating - especially quetiapine (Seroquel), which is popular as a sleep aid.
> I'd stay away from AP's, they're not worth the risks, unless you really need them.
>This is an overgeneralisation. Most, if not all, drugs and supplements are associated with certain risks. Depending on the choice of AP and dose, the risks are not higher- and can be lower - than with many antidepressants, stimulants, and other classes of medicines.
poster:undopaminergic
thread:832091
URL: http://www.dr-bob.org/babble/20080528/msgs/833165.html