Posted by linkadge on May 30, 2008, at 18:56:06
In reply to Re: Mirapex vs. Seroquel for SSRI-induced anhedoni » linkadge, posted by satsumas on May 30, 2008, at 18:29:22
>thanks...strange because i started smoking again >last week after coming back up on to effexor
>(after experiencing 4 weeks of suicidal >depression after coming off of emsam)...cravings >for cigarettes went through the roof and i gave >into them. now i'm half a pack a day :(Some studies have shown SSRI's / SNRI's can increase cigarette cravings. Perhaps the brain is seeking to restore the release of dopamine squelched by the AD.
>on emsam (which i was on before the effexor) i >felt I had way more "free will", wasn't as >addicted to the internet, and cigarettes were >not rewarding at all (actually quit before the >emsam, but tried smoking a few times and threw >away the rest of the pack).
Hmm. Perhaps the selegiline has some sort of antiaddictive properties. I think it raises GDNF, which like ibogaine can help reduce cravings.
>basically, the strategy in trying mirapex on top >of effexor is to replicate the good parts of >emsam (the pro-DA aspects) without feeling the >incredible anxiety and obsessive thoughts I felt >while on it (guess it didn't do much for >serotonin).
That sounds reasonable.
>also thinking about trying tianeptine instead of >effexor, perhaps with mirapex. just can't stand >how effexor makes me so emotionally blunted and >affectless. sometimes i wonder if i should just >go cold turkey on all ADs.
Thats an option. I don't know how it will fair with the OCD, but its worth a try. Somtimes a drug holliday can really help. It doesn't mean you need to stay permantnly off meds, but somtimes a washout can re-reveal the problems which need to be adressed.
Certain supplements too allow people to get by with less medication.
Linakdge
poster:linkadge
thread:832091
URL: http://www.dr-bob.org/babble/20080528/msgs/832133.html