Posted by undopaminergic on May 26, 2008, at 15:40:47
In reply to Re: Suggestions for non-benzo anxiolytics PLEASE.., posted by Molybdenum on May 25, 2008, at 19:54:11
> Thanks for all the suggestions undopa. I really appreciate it.
>
> >Be *very* careful about using moclobemide with venlafaxine. The combination has the potential to precipitate hyperserotonergia (serotonin syndrome), >and deaths have been reported. Make sure you have cyproheptadine at hand as an antidote, and take a tablet if you find your temperature on the rise, as >the condition can sometimes progress rapidly to the point where consciousness is lost.
>
> Yeah...I am a bit concerned. I've just taken my 3rd 150mg Moclobemide tab (over 3 days). I feel "slightly dizzy" but not enough to stop me driving, etc.
>Have you taken your temperature? And blood pressure?
>
> I'd never heard of your suggested antidote "cyproheptadine" so I looked it up & found that it also sounds like a good sleeping pill. In fact it says "cyproheptadine enhances sleep quality and quantity whereas benzodiazepines tend to decrease sleep quality". Only downside is that is causes sedation.
>Sedation is precisely what you want from a sleeping pill. On the other hand, when cyproheptadine is used as an antihistamine, which was the original intention, sedation would typically be undesirable.
>
> Opiates are very hard to get here on account of their abuse potential. I've taken 60mg codeine with paracetamol as a pain medication post surgery & found that it really affected me mentally. I know you'd like me to be more precise but the best description I can come up with is that I felt very "out of it". So I think I'll have to pass on the codeine.
>The effects - and side-effects - are dose-dependent. 60 mg is pretty much - my impressive anxiolytic experience resulted from less than 15 mg. I imagine that powerful opioids like morphine and oxycodone might be difficult to get, but the "minor" ones might not, unless you mention (or otherwise hint at) your interest in their mind-altering - as opposed to pain-killing - properties.
poster:undopaminergic
thread:830647
URL: http://www.dr-bob.org/babble/20080519/msgs/831227.html