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Re: Ok, Fluoxetine is the most stimulating SSRI...

Posted by marcus75 on September 22, 2007, at 14:58:05

In reply to Re: Ok, Fluoxetine is the most stimulating SSRI..., posted by Amigan on September 16, 2007, at 12:52:55

In my view it is the most stimulating because of its low affinity for the alpha-1 receptor (equilibrium dissociation costant is 5900). Fluvoxamine Ki is even higher, 7500, but it more sedating because it has higher affinity for H1.


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