Posted by Amigan on September 16, 2007, at 12:15:19
Greetings everyone.
I decided to register to this forum after i stumbled on it, while i was searching the net for informations on psychiatric medications and saw how informative it is. Very nice forum, although its layout seems a bit bizzare. :-P
My native language is not english, so you'll have to excuse any errors i will possibly make.Anyway, on the purpose of this thread:
I read from several, different sources that fluoxetine (prozac) is the most CNS stimulating SSRI. I don't doubt it, i just don't understand it..
It would be more logical to me to assume that sertaline, (zoloft) (and possibly duloxetine?) are more potent stimulants than fluoxetine, since they both possesses a weak inhibitory action in the reuptake of dopamine, while fluoxetine doesn't seem to have this property.
I'm sure that most of you know that inhibition in the reuptake of dopamine causes stimulation and that's what makes me to become confused about it.
What i would like, is a simple pharmacological explanation on why fluoxetine is the most stimulating SSRI.Thank you.
poster:Amigan
thread:783231
URL: http://www.dr-bob.org/babble/20070911/msgs/783231.html