Posted by linkadge on May 29, 2007, at 6:39:22
In reply to Re: Effexor and dopamine » cornfedboy, posted by Phillipa on May 28, 2007, at 21:29:24
Effexor will affect the monoamines in a fixed ratio that does not change with increaing the dose.
What people mean when they say the norepinephrine effects "kick in" at higher doses, is that for some people higher doses are needed before a noradrenergic effect is felt.
The drug will inhibit the norepinephrine reuptake pump dose dependandtly.
Depending on your sensitivty to it, some can feel the noradrenergic effects at very low doses.
The serotonergic effects do not stop at a certain dose either. The more drug, the more reuptake inhibition.
I don't know what dose one would need for a pronounced dopaminergic effect. Probably a LOT, as it is a very weak inhibitor of dopamine reuptake.Linkadge
poster:linkadge
thread:760068
URL: http://www.dr-bob.org/babble/20070524/msgs/760129.html