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Re: Upper+downer for Anx/dep

Posted by linkadge on December 24, 2006, at 12:09:11

In reply to Re: Upper+downer for Anx/dep » linkadge, posted by laima on December 23, 2006, at 16:53:10

>To clarify, are you saying valproate can help >protect the brain from possible damage caused by >using stimulants? Ie, help protect against >effects such as amotivation or apathy induced by >using stimulants?

Its hard to say. Wheather amotivation and apathy are induced by structural changes in the brain, or temporary biochemical alterations is the question.

I have never combined valproate with amphetamine or ritalin, but it may well be that the valproate blocks some of the effect of the stimulant as well.

I know that the two are often combined in bipolar comorbid ADHD, so there must be *some* advantage to adding the stimulant or else it wouldn't be done.

I would think that valproate could block the subjective wellbeing produced by stimulants, but I don't know the net effect of a long term combination of the two.

However, blocking sensitization produced by the drug would very likely help to preserve the effect of the drug.

I can't say much more as I havn't combined amphetamine or ritalin with valproate.

If you were to do so, I'd start with the lowest dose of stimulant as possable. I heard of a person combining marajuanna with dilantin who went on a magic carpet ride. Thought this is a slightly different combination :)


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URL: http://www.dr-bob.org/babble/20061224/msgs/716131.html