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Re: 5-ht2a » linkadge

Posted by janeB on July 16, 2006, at 9:34:37

In reply to Re: Do not fear Seroquel, posted by linkadge on July 15, 2006, at 21:24:54

> I think the antisuicide effects of antipsychotics is related to their effects on 5-ht2a. Clozapine is really the one antipsychotic that has been shown to produce a strong effect in this regard, and it has high antagonist affinity for 5-ht2a.

Doesn't Periactin (cyproheptadine) also have a high affinity for 5-ht2a? I have observed many recommendations that periactin be used for sexual problems but no recommendations for its use in insomnia. Why is this? Years ago (about 30) a neurologist prescribed periactin for trigeminal neuralgia and I had the best sleep in years while on it. Makes me wonder what klonopin targets because that is what has worked for me to sleep for the last 10 years. What do you think? Jane


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URL: http://www.dr-bob.org/babble/20060709/msgs/667464.html