Posted by SLS on July 15, 2006, at 12:03:13
In reply to Re: Seroquel is a MIRACLE drug for Insomnia » SLS, posted by Crazy Horse on July 15, 2006, at 9:57:51
> > > Oh yeah, what dose? 25 mg is the smallest dose they make. You can even cut it in half. You will feel Seroquel the first day you take it and not have to wait 4-6 weeks.
> >
> > Do you find it to be true that Seroquel begins to lose its hypnotic effect the higher one raises the dosage?> Isn't Seroquel an atypical antipsychotic? Antipsychotics scare me because of the possibility of developing Tardive Diskinesia. Is the probability high (just a rough estimate) of developing T.D. on seroguel? Thanks.
The risk of developing TD might be lowest for Seroquel, although some people will argue that Clozaril is lowest. Seroquel has the lowest binding affinity to the D2 receptor. It hops on and hops off very quickly and is thought not to provoke the induction of the supersensitivity that is thought to be responsible for the production of TD.
I am not as afraid of TD with the atypical neuroleptic drugs as I once was. Risperdal is the only one I would worry about at dosages exceeding 6mg. However, EPS has been reported with every neuroleptic drug, and I have to believe that even Seroquel is capable of producing TD and NMS.
I am ambivalent about the use of Seroquel for insomnia and other antipsychotics for indications other than schizoid conditions. I use them because I have few alternatives. They do have antidepressant and anti-suicide properties. Seroquel is sometimes the only drug that will treat insomnia effectively. It is not the ideal solution, but mental illness is not the ideal living condition.
- Scott
poster:SLS
thread:667214
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