Posted by linkadge on July 15, 2006, at 21:24:54
In reply to Re: Do not fear Seroquel, posted by UgottaHaveHope on July 15, 2006, at 21:03:38
I think the antisuicide effects of antipsychotics is related to their effects on 5-ht2a. Clozapine is really the one antipsychotic that has been shown to produce a strong effect in this regard, and it has high antagonist affinity for 5-ht2a.
There seems to be altered expression of the 5-ht2a receptors in suicide, whereas disturbances in d2 etc have not been noted in suicide.
Linkadge
poster:linkadge
thread:667214
URL: http://www.dr-bob.org/babble/20060709/msgs/667396.html