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Re: I want to go back on Parnate.

Posted by alone ranger on May 7, 2006, at 18:13:30

In reply to Re: I want to go back on Parnate., posted by tygereyes on May 7, 2006, at 17:53:48

> > > ... thank you, alone ranger, for the information.
> > >
> > > I should also add that my psychiatrist mentioned that this is an underreported side effect (though it is listed in the full prescribing information) with Parnate.
> > >
> > > Both she and my dermatologist have agreed that Parnate was the culprit in causing this problem.
> >
> > Tygereyes,
> > I believe you about Parnate causing the acne. There's just this continuous undereporting problem of side effects and most docs use the pdr as the holy grail. In the past few days, the FDA has now esatblished sustained hypertension with Effexor and effexor XR in some folks after several reports.
> > I don't understand why your doctor put you on Emsam with your interstitial cystitis. The insert clearly inicates urinary tract infections and frequent urination under the urogenital section. Is there any way you can add on Neurontin, low doses cylosporine, or oral Pentosan Polysulfate which have been effective in treating your disorder? Maybe you've already tried these in the past without any luck. I don't have an answer as to why the Parnate is causing the acne. The abstract I sent you was dealing with treating challenges to resistant acne. I'll holler if I find an answer for you.
> >
> >
>
> My worst IC symptom is (embarrasingly) bed-wetting. Neurontin caused this to happen AND made me stupid on top of it.
>
> Elmiron (pentosan polysulfate) didn't help, and made my hair fall out. :-/
>
> Also, most drugs have "urinary frequency" listed as a side effect - even Parnate, which basically cured my IC. It is impossible to tell which drugs will activate it.
>
> Drugs that caused bed-wetting included: ALL SSRIs & SSNRIs, Trileptal, Seroquel, Lamictal, Zonegran, Topamax, Risperdal, and Zyprexa. Some of these meds could be "balanced out" with tricyclics, such as Trileptal and Seroquel. The others could not - even with high-dose tricyclics, I was experiencing bedwetting. The SSRIs/SSNRIs were the worst offenders.
>
> I was shocked when Parnate didn't cause it - and even enabled me to take Seroquel and Ambien, drugs that otherwise would have caused bedwetting! It "cured" my IC - or at least brought me as close to a cure as I will ever get. No bedwetting, no pain, no frequency, no urgency ... it was wonderful. And a total surprise, being that Parnate is so rarely prescribed and IC is so rarely diagnosed that to find someone with both would be unusual (not to mention, the journals probably wouldn't publish such a case study anyway.)
>
> I was hoping that EMSAM, being a MAOI, would be similar in not causing bladder problems. However, I am still taking Seroquel and Ambien and it is possible that it is these two drugs that are causing the recent problems, now that I am no longer on Parnate. I am going to try 9 mg/24 hr as an experiment with mood and with IC symptoms and, if either of those don't improve, will go back to Parnate and find some way to manage my skin.

Willyee raises an excellent point. Had you ever tried quickly washing the red coating off the tabs?


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poster:alone ranger thread:640594
URL: http://www.dr-bob.org/babble/20060504/msgs/641063.html