Posted by linkadge on March 19, 2006, at 18:41:39
In reply to Re: CFS and tianeptine SLS, posted by SLS on March 19, 2006, at 9:07:50
I've personally been interested in tianeptine. It many of the rat studies tianeptine show a much more robust ability to protect certain brain structures from the consequences of unavoidable stress, than other antidepressants.
I expereineced a rebound improvement in depression after discontinuing SSRI's, TCA's and MAOI's. Infact, I went into a complete remission for about a month after stopping Parnate.
They're doing a lot of reasearch regarding the SERT molecule, and weather or not it is actually overactive in depression.
Some studies have shown that the opposite is true. Individuals carring a double short varient of the serotonin transorter, (which codes for lower serotonin reuptake) acutally had a higher lifetime prevailance of major depressive disorder.
We also have some drugs that act as serotonin uptake inhibitors, but have little to no antidepressant effect.
It's really a mystery to me.
Linkadge
poster:linkadge
thread:620471
URL: http://www.dr-bob.org/babble/20060315/msgs/622205.html