Posted by tessellated on March 3, 2006, at 17:51:27
In reply to Re: Worst visit ever.......... » willyee, posted by Chairman_MAO on March 3, 2006, at 13:47:08
i'm not one for conservative approaches, but i can mention that i had one of the more unfortunate, though totally fascinating, and expensive side effects from high dose (self prescribed) parnate: PSYCHOSIS. I believe that at high doses over 100mg, it does begin to function quite like amphetamines, triggering the dopamine receptors quite heavily and causing a supersensitivity. i think they can begin almost to self stimulate creating a dream/awake stake.
i don't know if the psychotic break was from stopping parnate, or upping it. this is common with ampetamines (and used to induce models of schizo in rats in order to develop antiPsychotics). Aside from being locked up and force administered seroquel, i would not persononally take that road again.
psychosis is not like simply hallucinating off a typtamine, fungi, or cacti, etc...it's like being those dudes in the middle of traffic talking to invisible people, tweakers as they say.
i have no idea what dose i was up to, no how long i went without sleep, though i would expect around 150mg/day. now we all have dif physiology, but there is a rule: you have to pay to play.
with this med as with others it does require respect, as it is a valuable agent. i myself would not want the task to oversee someone at the 150mg level unless they were in patient-
think about the worries, the possibilities, the random unknowns...ideally meds are a stop gap. get you to the next pay check. etc. to look at them as being necessary for years should not be a default decision rather only pure serious desperation.
The mind is a truly wonderous and resilliant organ with amazing self healing capacity if given the chance.
Give it that.
> I feel for you. I really do. What you described is a travesty and I really do not know what to say except that I am in a similar situation myself.
>
> The maximum safe dosage of tranylcypromine is actually _180-200mg/day_. Most psychiatrists are utterly incompetent and have less knowledge of pharmacology than a first-year pharmacy student, it seems.
>
> I have a feeling you are looking for something that no dose of parnate is going to provide. The good effect will last longer at 200mg/day, but you will eventually crash at some point. Please try Nardil 1mg/kg if at all you can. Forget the side effects right now. I have learned that the hard way.
poster:tessellated
thread:614865
URL: http://www.dr-bob.org/babble/20060227/msgs/615554.html