Posted by zeugma on February 26, 2006, at 12:50:20
In reply to Re: provigil discussion, posted by SLS on February 26, 2006, at 9:11:37
the mechanisms by which modafinil improves depression (usually implemented as an augmenting agent) might involve the shifting of thalamic glutamate/GABA balance towards glutamate and the subsequent activation of DA neurons in the nucleus accumbens.>>
Modafinil also elevates serotonin levels in cortex and dorsal raphe, which is surely relevant to depression.
-z
poster:zeugma
thread:612884
URL: http://www.dr-bob.org/babble/20060219/msgs/613461.html