Posted by zeugma on November 1, 2005, at 19:47:29
In reply to Re: DPSP database clomipramine dopamine affinity, posted by linkadge on November 1, 2005, at 17:28:35
> One of the reasons that clomipramine is so effective (in my bitter opinion :) ) is that it is a high octane dumb drug.>>
anticholinergic effects can impair memory, but I seriously, seriously doubt that memory impairment is the mechanism by which they may contribute to alleviation of depressive states.
Klonopin can cause serious memory impairment, and yet it has a reputation for causing depression. And drugs that enhance memory, such as anti-Alzheimer's drugs, whose pro-cholinergic effect is the opposite of clomipramine's, are notably ineffective in treating depression, and appear to be even more depressant than Klonopin.
-z
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poster:zeugma
thread:573553
URL: http://www.dr-bob.org/babble/20051031/msgs/574283.html