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Re: DPSP database clomipramine dopamine affinity

Posted by zeugma on November 3, 2005, at 18:31:57

In reply to Re: DPSP database clomipramine dopamine affinity » rod, posted by ed_uk on November 3, 2005, at 16:57:30

> LOL Roli, are you gaga?
>
> Ed!

Hi Ed,

Online diagnosis is a tricky thing, but I suspect Roland of liking his TCA's a little too much. Consider this strange report:


Przegl Lek. 2005;62(6):397-8.


Recreational amitriptyline abuse.

Sein Anand J, Chodorowski Z, Habrat B.

1st Clinic of Internal Diseases and Acute Poisonings, Medical University of Gdansk, Poland. jsanand@amedec.amg.gda.pl

Amitriptyline is a potent anticholinergics, rarely used as a drug of abuse. Two cases of amitriptyline dependency lasting for almost twelve months were described. According to the patients the abuse with amitriptyline guarantee them safety not to be uncovered by parents and doctors who systematically checked their urine with typical narcotic tests. CASE REPORT: Two patients with a history of abuse with amphetamine and clonazepam were admitted to the Clinic because of intoxication with amitriptyline. They denied the suicidal attempt and explained that they used amitriptyline in a dosage of 100 to 200 mg per day as a drug of abuse. On the day of admission one of the patients had increased the dosage up to 600 mg which caused an acute intoxication. CONCLUSION: Antidepressants should be treated as a drugs with possible abuse ability.>>

I wonder if the writers of this article were amitriptyline abusers themselves.

:-)

-z


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poster:zeugma thread:573553
URL: http://www.dr-bob.org/babble/20051031/msgs/575109.html