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Re: Reserpine for depression

Posted by zeugma on September 9, 2005, at 18:21:36

In reply to Re: Reserpine for depression » SLS, posted by Ilene on September 9, 2005, at 15:49:59

hi Scott,

you are a true troublemaker- I had sworn off the med board, but this thread is too delicious.

There was a study done in the mid 50's at the Maudsley psych hospital that was one of the first randomized placebo-controlled tests ever conducted on depression- and the result was the that the drug was an anxiolytic and antidepressant. The drug also had a reputation as a neuroleptic and was used as such by Nathan Kline, discoverer of the AD effects of the first MAOI.

On the PI sheet for nortriptyline, it is reported that reserpine in combination with a TCA can produce a 'stimulating' effect.

Now that I've gratified you with historical arcana, can either you or linkadge (or possibly Chairman MAO) explain how modafinil works. Other than the headache-inducing effects it shares with MSG-laced Chinese food. The local No.1 Chinese Restaurant never did much for my wakefulness.

-z


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URL: http://www.dr-bob.org/babble/20050909/msgs/552857.html