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Re: Effects of Selegiline's amphetamine metabolite » christophrejmc

Posted by cache-monkey on April 23, 2005, at 13:23:25

In reply to Re: Effects of Selegiline's amphetamine metabolite » cache-monkey, posted by christophrejmc on April 22, 2005, at 19:36:43

<< L-amphetamine and l-methamphetamine primarily affect the peripheral nervous system (as opposed to the d- isomer which affects the CNS more), leading to side-effects like agitation, insomnia, hypertension, tachycardia, tremor, nausea, and anxiety (I do not know how frequent these side-effects are, you can check rxlist.com). These side-effects usually do not cause problems unless the dose is greater than 5mg. >>

Grr on the side effects. Anxiety, agitation and insomnia are a problem for me as it is. But I'm looking to possibly go on a mood stabilizer that's beneficial for those before starting an AD. Currently on Depakote. Not quite sure what the deal is right now, but if this doesn't work out maybe Seroquel would be a good way to counterbalance the selegiline in the evening.

<< I was smoking before I took selegiline and had no intention to quit, but I couldn't stand smoking while on it. The effect is really quite remarkable. >>

This is good to hear. I think I've been self-medicating a low-grade dysthymia with cigarettes for most of my adult life. I think that other than a mood-stabilizer, I'm looking for a light AD to a) treat my dysthymia and b) help me quit smoking. I didn't like Wellbutrin so much, and my pdoc is receptive to low-dose selegiline...

Anyway, thanks for the input!

Best,
cache-monkey


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