Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Why does nicotine solve all my psychiatric pro » linkadge

Posted by rod on April 3, 2005, at 13:10:06

In reply to Why does nicotine solve all my psychiatric problem, posted by linkadge on April 3, 2005, at 11:01:59

> Nicotine is by far the best antidepressant I have taken. It helps my anxiety and my motivation without causing any side effects. It supposedly is a potent 5-ht1a agonist.
>

cool !

> Why cant we just have a really strong 5-ht1a agonist. Why load numerous receptors with serotonin when only one needs it ??
>
>
> Linkadge

Hmm correct me if a am wrong, but as far as I know (a doc once told me), the different SSRIs have also different affinities within the 5-ht receptor family. Citalopram for example, has the biggest diffenerce in affinity to the 1A versus the rest (it "prefers" the 1A reuptake pump). Prozac ist the most unselective of the SSRIs.
I have read (but cant find the link) that even Clomipramine "prefers" the 1A receptor more than the other ones like 5-ht5, h-ht7 etc. The "selective" in the term SSRI does not mean its a serotonin only drug but it has selective effect within the 5-ht receptor family.

Maybe someone knows something like a chart, with the affinities within the 5-ht family for different drugs are listed?

And correct me if I got fooled by this doc :-)

Roland


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:rod thread:479258
URL: http://www.dr-bob.org/babble/20050330/msgs/479302.html