Posted by jujube on November 1, 2004, at 10:54:21
In reply to Re: no more Cymbalta for now » karaS, posted by zeugma on October 31, 2004, at 19:54:19
Z,
If you don't mind my asking, are you taking anything else with the Provigil? I am on my fourth AD trial in less than a year, and it is not doing a thing for me. I have a pdoc appointment tomorrow, and am researching options. I have Provigil on my list as a possible augmenter (not sure if the pdoc will go for it. He seems averse to augmentation.). So far I have tried Paxil, Prozac, Effexor (up to 225 mg) and now Celexa. I am thinking it may be time to go to a TCA, but am scared stiff because of all of the side effects. However, if a TCA will bring me out of the black hole I'm in, then maybe that's the route I will have to go. Do you know if you can combine Provigil with a TCA?
Thanks, and sorry for butting into the thread with all my questions.
Tamara
> > > You're welcome. Your questions are also helpful to me. Has the Cymbalta done anything at all for you yet?
> > >
> > > -z
> >
> > I'm off of the Cymbalta completely now. I couldn't tolerate the side effects in my present situation. Also, I am afraid of using anything serotonergic (without a dopaminergic) right now that might possibly make my dopamine problems worse. I may reserve the right to try it again at a later date. I just have to figure out what to do next. I have been thinking of Parnate though that would probably also put me to sleep - at least initially. (I'm basing this on the fact that selegiline does and they're very similar). OTOH, I read/posted an abstract recently that spoke about its ability to downregulate those DA autoreceptors. I might have to deal with some major fatigue for a while to get the therapeutic effect.
> >
> > Most likely I'll just sit here thinking about this and changing my mind a million times before I do anything.
> >
> > How are those purple dancing elephants?
> >
> > K
>
> The purple dancing elephants are OK. But they make a lot of noise :)(plus it smells like a circus in here).
>
> Parnate sounds like an excellent idea. You might have to deal with the fatigue, and the dietary restrictions, but most sources say Parnate has fewer s/e than Nardil.
>
> Right now I'm in a fallow period. I'm positive, given my response to provigil and the recent discoveries of orexigenic transmission, that many of my problems localize in the hypothalamus. I plan to spend the coming months researching this in my spare time.
>
> I took a 'holiday' from Ritalin today (only 20 mg). I feel completely exhausted.
>
> -z
poster:jujube
thread:406397
URL: http://www.dr-bob.org/babble/20041029/msgs/410031.html