Posted by zeugma on July 4, 2004, at 11:37:01
I am suffering from a bout of (intensified) vegetative depression, which does not come completely as a surprise to me, as I tend to fall apart completely when not working (I teach and it's summer break). I was depressed when working, but it was mitigated by the need to function and interact with others. Now i feel completely adrift and lethargic. I am going to give my AD one last chance, by raising the nortriptyline dose from 75 to 100 mg tonight.
I also take Provigil, 100 mg, and it has absolutely no energizing effect whatsoever. But I don't think I'll have given it a fair trial until I've gotten to 200 mg. If nothing else, 100 mg nortriptyline should counteract the Provigil insomnia (ironic that a drug that is not energizing should make it harder for me to sleep). From my experience, nortriptyline is the reverse of a drug like remeron (it gets more sedating as the dosage is increased). I also have Lexapro samples but don't think much about Lex as a treatment for vegetative depression. What gives me a little hope is that I have read studies suggesting that there is a window within the window for nortrip plasma levels (about 80-120 ng/mL, within the larger window of 50-150 ng/ml) at which nortrip becomes its most effective. I hope this pulls me out of this depression.
poster:zeugma
thread:363009
URL: http://www.dr-bob.org/babble/20040704/msgs/363009.html