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Re: amitriptyline, fluoxetine toxicity » chemist

Posted by rod on April 11, 2004, at 4:46:23

In reply to Re: nortriptyline, citalopram toxicity » Vera, posted by chemist on April 10, 2004, at 21:27:22

Hi chemist,


sorry for sneaking in and starting an off topic question.
You really seem to know a lot about the enzyme interaction issues. So I have to ask you the following.
I once were taking 75mg(and for some time 100mg) of Amitriptyline and 40mg Prozac (thats the strongest 2D6 inhibitors of the SSRIs, as far as I know). I really felt extremely worse on that combo and after I did quit cold turkey and switched to celexa alone, and I felt better very very fast. And even my doctor, although he didnt seem to be aware of the enzyme interaction said:"hmm, it seems there was something wrong with the medication".
Do You know, if the administered dosages were high enough to get toxic amitriptlyine levels?

Thank You very much!

Roland

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