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Re: Doxepin v Mirtazapine

Posted by scott-d-o on February 4, 2004, at 16:00:07

In reply to Re: Doxepin v Mirtazapine » scott-d-o, posted by Sad Panda on February 4, 2004, at 3:01:37

> No Scott, you missed your own point. Anything Doxepin can do, Mirtazapine can do better. Neither drug has any dopamine effects, so why are you talking about Parkinson's & Schizophrenia?? Mirtazapine is a mild anti-depressant that can reverse SSRI induced side-effects & give a good nights sleep, Doxepin is similar, but not as good.
>
> Cheers,
> Panda.
>
>

how can you say they are similar when one is a tricyclic that works by blocking reuptake of serotonin and norepinephrine, and the other works by antagonising postsynaptic serotonin receptors? they are hardly alike at all..

I brought up dopamine antagonism as an *example* of how the same action at a receptor can harm one person and help another.


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URL: http://www.dr-bob.org/babble/20040204/msgs/309408.html