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Re: I NEED A DESIGNER DRUG ASAP!!!!!! It will.....

Posted by scott-d-o on January 29, 2004, at 0:50:55

In reply to I NEED A DESIGNER DRUG ASAP!!!!!! It will........., posted by Betternow on January 29, 2004, at 0:10:43

> antagonize 5ht2a, agonize 5ht1a, it could have some reuptake inhibition-5ht and/or NE. IT MUST NOT effect alpha1 adrenergic receptors, the cholinergic muscarinic receptors, or the histamine H1 receptors.Geodon is close but its alpha1 antagonism kills it for me. I cannot do alpha blockers, they make me a stupid zobie with a bad case of sinusitus.
>
> In the abscence of such aperfect drug, Anyone have any ideas on counteracting the Alpha1 adrenergic antaganism present in drugs like serzone, geodon, trazadone, mirtazapine, etc. It is that property of these drugs that make us feel like crap.
>
> Has anyone got an idea on how to counteract. Could one take an Alpha1 adrenergic AGONIST to offset?
>
> Sick and tired of the SSRIs-gotta find alternative
>
> Not so Betternow
>


here u go:

http://www.biopsychiatry.com/flibanserin.html

no reuptake inhibition... but one med can't do everything, can it?


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poster:scott-d-o thread:306751
URL: http://www.dr-bob.org/babble/20040127/msgs/306754.html