Posted by craig allen on September 14, 2003, at 0:28:11
In reply to Rant, posted by Questionmark on September 13, 2003, at 22:45:24
i'm with you on the rant. the problem of tolerance with opiates is huge however. my experience is that within days, they stop being effective and the doseage continually needs to be increased. as this happens, the withdrawal becomes a constant battle and before you know it, you're in a bad addictive cycle and the depression is a lot worse than it was before. until they develop a drug that eliminates this tolerance process, the opiates aren't going to improve depression long term. they make it much worse. i'm not speaking from a theoretic perspective - i'm basing this on experience. a lot of it. the potential good news, i guess, is that some drugs are in the works. i looked at the website one of the previous posters suggested, Pain Therapeutics, and they are at least claiming to be on to something. if they are, then the battle will be getting psychiatrists to prescribe it. i'll believe all of it when i see it. has anyone been on a long acting opiate with low dose naltrexone? apparently, that is what Pain Therapeutics is developing (a combination drug). if so, how did it work?
poster:craig allen
thread:120871
URL: http://www.dr-bob.org/babble/20030912/msgs/259823.html