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Opioids and Depression

Posted by BrittPark on September 23, 2002, at 20:05:59

In the past this subject has resulted in flame wars. I think it's an important topic so I'm bringing it up again. I'm interested in hearing about as many experiences as possible, both bad and good, with opioids for depression. In particular I'd like to see what doses people have taken of which opiates, whether dose escalation was a problem.

I'll start the confessional now. I've had recurrent major depressive episodes for the last 20 years ago. About 1 year ago when I was having another Depressive episode I suggested to my psychiatrist that a low dose of vicodin might be helpful. I'd read Dr. Bodkin's results with buprenorphine, and had experienced a marked improvement in mood when taking vicodin for pain post-operatively in the past. My psychiatrist (bless his soul) said why not, and prescribed me 1 vicodin/5 per day. I found that 2.5 worked just about as well as 5 and took that dose regularly in the evening with good results. More recently I moved up to 5, with my doctor's approval. Whether from tolerance or from poorer affect I don't know. Vicodin works well for me but only for the 4 or 5 hours after I take it. I'd take 4 vicodin/5s a day in a minute if I knew I wouldn't become tolerant.

Now tell me your experiences.


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poster:BrittPark thread:120871
URL: http://www.dr-bob.org/babble/20020922/msgs/120871.html