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Re: Buprenorphine-- bee happy » bee happy

Posted by SLS on February 18, 2003, at 21:16:16

In reply to Re: Buprenorphine-- bee happy » SLS, posted by bee happy on February 18, 2003, at 18:30:07

Hi Bee.

Thanks for your detailed reply.

> So, what's your story?

I suffer from a severe anergic depression that is probably a form of bipolar disorder. Dementia (general definition) is probably the most prominent symptom cluster right now. Without the partial relief I glean from Lamictal + desipramine, I cannot read more than two or three sentences before having to quit or go to sleep. My thoughts are very slow and muddied, and my memory is terrible. The few manic episodes I have had were precipitated by drug intervention. Without an effective treatment, I remain depressed continually. Since 1982 (age 22), I have never experienced a spontaneous remission. The only robust (nearly complete) response to treatment came in 1987 and lasted 9 months. I would most likely be OK today had my doctor at that time not opted to discontinue the drug combination (Parnate + desipramine) due to the emergence of mania. Once the mania was under control using lithium and Klonopin, he decided not to restart the antidepressants. I relapsed within two months. Instead of returning to the previously effective medications, he gave me the newly-approved Prozac to try. I guess it was a new toy. To make a long story short, I have not responded to anything since - not even the original MAOI + TCA combination. It is an unfortunate mistake that some people make to discontinue a particular drug, only to go on to relapse and find that their first exposure to the drug has rendered their brain less responsive to it.

I have been on most of the drugs currently available and many that remain unavailable (foreign and investigational). So, yes, I am very interested to pursue the use of opioids should the next few drug trials I attempt fail.

Among the drugs I have tried are:

Parnate
Nardil
imipramine
desipramine
nortriptyline
amitriptyline
amoxapine
protriptyline
lithium
Depakote
trazodone
Wellbutrin
indalpine
viqualine
Prozac
Paxil
Lamictal
Neurontin
Tegretol
Zyprexa
Risperdal
Effexor
clorgyline
idazoxan
nomifensine
adinazolam
bromocriptine
Cytomel
Synthroid
pemoline
Ritalin
Dexedrine

I have a list somewhere.

- Scott

 

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URL: http://www.dr-bob.org/babble/20030214/msgs/201693.html