Posted by ace on January 7, 2003, at 22:55:05
In reply to Re: NARDIL: onset of action - please answer!, posted by djmmm on January 7, 2003, at 8:59:07
> I noticed a profound difference in a week or two...FWIW, Parnate should be included, along with Remeron and Effexor as "faster" onset antidepressants.
Djmm - were the effcts all in one? Or did they come slowely in addition to your first therapeutic 'zap'?
> I believe MAOIs have tested faster because of some evidence they have a direct effect on the stimulation of catecholamines. Effexor and Remeron are unique in that they effect the opioid system.
How can you explain those who it takes 6-8 weeks? Faster acetylators? (Nardil being metabolized for the most part by acetylation)
Do you believe some people NEED 90mg to inhibit 85% (thereaputic effect) of MAO?
Have you personally heard stories of long thereaputic lag-time?All the very best.
poster:ace
thread:134761
URL: http://www.dr-bob.org/babble/20030106/msgs/134904.html