Posted by BK on September 12, 2002, at 23:41:10
In reply to Nardil lasts - but like benzo, taper up 3 months, posted by chad_3 on September 9, 2002, at 23:54:24
> JohnQ -
>
> I believe that many people stop taking Nardil due to it "stopping to work" - but the only cases of that I've ever heard occur early on - in the first few months. It is actually very common for Nardil to work good initially at a low dose, only to "stop working" for SP - this is when the dose is raised (this is much the same as Klonopin is ramped up for long term use). In my case for example, I started Nardil (my first time ever) - at 45mg to good effect quite soon. After 2 or 3 weeks - nothing. My Dr. raised to 60. Again - euporia and anti-SP. 2-3 weeks goes by. Suddenly nothing. In my case - which was very severe since about age 19 - I ended up going to 90mg, at which point lasting effect was maintained. By that time, I had sexual side effects which I complained about. My Dr. reassured me, weeks on end. And he was right. But the literature (which is hard to find for this underutilized but old drug) - does indicate this is the norm.
>
> The main problem is Dr's stopped prescribing MAOI's after a cheese scare and also the SSRI's and still today most Dr's don't know even the basics of how to prescribe it correctly - including that SP may require higher doses than mild depression - (true with SSRi's as well - though their efficacy is much lower and in long term side effects of Paxil and Zoloft significantly worse IMO).
>
> It is a little bit risky to look for advice on "what works" on a board like this - as those getting the most effective results are busy elsewhere. That is why I suggest the books at the base of my webpage - and I admit data on Nardil is hard to find - there is simply no $$$ whatsoever in promoting this drug for SP. Drug companies are billion dollar businesses.
>
> Oh - BTW, most a/d's I don't hear of "poop out" - except 1. I've heard several people tell me that Paxil "worked really well" for their SP for usually about 1 year or so - then "pooped out". I have no idea why that occurs. But most of the results I have heard from Paxil for pure generalized SP have not been good.
>
> Nardil is kind of like a benzo - and maybe tricyclic (not sure - I never took those) - but the dose tends to go medium to high - and requires slow increase - if it works a few weeks and stops - then it is time to increase the dose.
>
> Anyway - this is my view. Thanks for the feedback and best wishes!
>
> Chad
> http://www.socialfear.com/
>
> > Chad,
> >
> > Do you have any idea of what the "poop-out" rate for Nardil would be? It seems like most of the people here that have tried Nardil have had it quit on them eventually. I'm thinking of trying it, but that seems to be the major sticking point for me. Thanks.
>
>
Chad,I took Nardil some fifteen years ago and initially it was an absolute godsend in terms of relieving my SP. Unfortunately, after three months it completely pooped-out. I tried increasing the dosage (I believe to 90 mg) and I got hand tremors so severe that I couldn't feed myself. My SP worsened considerably at this point. Regrettably, I had to give up on the drug at that point. Several years later I retried the drug and I just didn't experience anywhere near the benefits that I had initially.
I truly believe from reading the postings herein that there is indeed a high incidence of Nardil poop-out, and in my particular case, increasing the dosage did little to stop that. I'd be very interested (and very appreciative) if anyone knew of a safe and effective agent that could be taken in conjunction with Nardil to increase its efficacy.
poster:BK
thread:119071
URL: http://www.dr-bob.org/babble/20020906/msgs/119696.html