Posted by Ritch on January 26, 2002, at 0:50:49
In reply to Re: re: adrafinil Alertec (provigil) avail in Canada » 3 Beer Effect, posted by IsoM on January 25, 2002, at 20:37:56
Hi, IsoM,
I see that Provigil is now avail. in Canada. I saw my pdoc this week and my idea was not well received (swapping my low-dose Wellbutrin for low-dose Provigil). I read the posts about the liver probs. I read the monograph for modafinil and it doesn't appear to be very *liver friendly*. The CYP3A4 situation is likely to tinker with my clonazepam and citalopram blood levels. Also, I noticed that they enrolled only *healthy* volunteers-nobody had any dx other than narcolepsy for the trials. I wonder if they gave modafinil to a random sample of the general population or in a trial for depression how different the side-effect profile might be??
I am willing to try it the next time (my pdoc is considering), but I wonder if could be a bad idea for comorbid bipolars.
Mitch
poster:Ritch
thread:91490
URL: http://www.dr-bob.org/babble/20020124/msgs/91648.html