Posted by MB on January 25, 2002, at 21:11:46
Even with Klonopin (2mg/day) and LARGE doses of Neurontin (400mg 5 x day) I'm still getting breakthrough akathisia from the Prozac I'm on. I'm also taking 5 mg of Adderall, but that actually *helps* the akathisia. I think the akathisia is from the the way prozac stimulates 5-HT(sub)2 receptors, which in turn antagonizes dopamine action in the striatum. Do you think that if I switched to Serzone (which blocks 5-HT(sub)2 receptors and hence increases striatal dopamine) I would have less akathisia? I've suffered Restless Leg Syndrom all my life and this exacerbation is driving me loony-toons.
MB
poster:MB
thread:91621
URL: http://www.dr-bob.org/babble/20020124/msgs/91621.html