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Re: Which benzo is *least* sedating? +other stuff » Elizabeth

Posted by Mitch on November 3, 2001, at 12:46:20

In reply to Re: Which benzo is *least* sedating? +other stuff » Mitch, posted by Elizabeth on November 3, 2001, at 10:54:26


> > The trick is to get me ATTENTIVE *and* CALM. I can get one or the other fairly easily, but BOTH is *THE* problem!
>
> ADD + anxiety/agitation is really tough to treat, but I think MAOIs might be effective.

Elizabeth, I would definitely agree but my current pdoc won't touch them-nyet, no, nada (and perhaps for good reasons)! I even mentioned selegiline and NOPE to that one as well. Is SJW really much of an MAOI inhibitor or is most of that just BS? I was told it would be ok to experiment with that somewhat.

>
> > From personal experience, yes, Klonopin/Ativan/Xanax does the trick for panic, BUT, just ordinary anticipatory GAD-like angst- chlordiazepoxide or diazepam seemed to work much better-I think you are onto something there.
>
> "Onto something?" I was disagreeing with you!

OOPs! There's my ADHD sneaking in again.

> I don't know. If you were experiencing that, I would expect your blood pressure to be quite high. I've experienced actual hypertensive crisis (due to MAOI-food interaction) and what you're describing doesn't sound much like it at all.

Well, my BP *is* much higher while taking NT or Zoloft or Effexor (not a hypertensive crisis by any means-and different sfx)! It is normal if I am not taking those meds. It is borderline high when I am taking them. (118/70 > 145/80)
All I know is that the "cold nose", clammy hands, etc. were just like when I take pseudoephedrine for a cold. Also, when I was taking Adderall (just 5mg AM)-I coud jump on a stairmaster and I would get really nasty headaches in the back of my head.


>
> Did the side effects last long (more than a few weeks, say), or were you unable to tolerate the nortriptyline long enough to find out?

They were tolerable but very annoying. The Zoloft+Nortriptyline combo works fairly well for attentiveness. *If* the antihistaminic effect of the NT wasn't there it would probably be nearly ideal.

>
> > No Remeron for this dude again! For some reason anything that is an alpha-2 adrenoreceptor antagonist makes me VERY hostile and irritable.
>
> Alpha2 blockade leads to increased NE firing. But again, this is just speculative. What other drugs have caused that problem for you?

Buspar(even worse than Remeron). I was told (I think by JohnX2) that its primary metabolite is also an alpha-2 antagonist.


>
> > > How much morphine were you on?
> >
> > Oh, I have no idea! They started to give me a Vicodan when I got back to the observation room, and hey my throat is sore you know??, so they gave me a morphine shot in the but.
>
> Oh, it was IM. Injected morphine can hit pretty hard -- its bioavailability is a lot better when it's given parenterally than orally. And you were basically opioid-naive, right? (Never taken them long-term or anything like that?) Had you had nausea from opioids before?

No, I never had to take any opioids long term. Yes, the Vicodans they sent me home with *did* make me a little nauseous, but it was tolerable.

>
> > I just got back from surgery and my mouth was practically glued shut from all the anticholinergics they use,
>
> Morphine won't make *that* any better! I get horrible dry mouth from buprenorphine (morphine and hydrocodone caused it too).
>
> > and I was asked if I wanted to eat some soft food, have some juice, etc. I really *did* feel hungry! No nausea at all! I didn't know about the Odansentron until I got the statement from the insurance a couple of weeks later.
>
> Weird that the specific drugs you were given were listed on your insurance statement.

Ooops again, it wasn't the insurance statement it was the itemized statement from the *hospital*.

>
> I find that opioids make me hungry, although that might just be due to relief of depression.

Yes, I would agree with that.
Mitch

>
> -elizabeth


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poster:Mitch thread:82248
URL: http://www.dr-bob.org/babble/20011025/msgs/83081.html