Posted by Elizabeth on November 1, 2001, at 14:43:29
In reply to Re: Which benzo is *least* sedating? +other stuff » Elizabeth, posted by Mitch on October 31, 2001, at 23:28:28
> Wow! I used to get by OK on 10mg tid! Of course, I am med sensitive and it generally takes about 1/6 to 1/3 of anything to do the same thing for me that it takes for other folks.
I've heard many people say they are generally sensitive to meds. I wonder how that could come about (other than something major like liver disease).
> It is true that the low-potency benzos work better for GAD symptoms.
I've never seen any data to suggest that. Klonopin, Ativan, and Xanax have all been found effective for GAD as well as PD.
[re nortriptyline side effects]
> Mainly cold extremities (cold nose/hands, ie.), also got some facial numbness on the front of my face and forehead (that was like high-dose Gabitril in some ways). Also, my arms and legs would go to sleep easily and get numb and tingle. A little bit of tachycardia as well.Huh. Those are pretty weird, except for the tachycardia. I wonder what was going on there.
> BTW, I am thinking about starting a thread regarding Odansentron (ZOFRAN). It is a selective 5-HT3 antagonist which is used for chemotherapy/radiotherapy/postsurgical nausea and vomiting from the chemo drugs or from anesthetics/opioids.
It's bloody expensive, too.
> I heard somewhere that it decreased alcohol cravings in some people dramatically-also if my theory is correct it should be able to reduce nausea/diarrhea from SSRI's as well.
Sure -- so would augmenting with Remeron. I think Zofran was being studied as a possible anxiolytic, too, but I don't think anything came of it.
> I haven't brought it up to my pdoc just yet. I was given Odansentron immediately after my thyroid surgery and I was sitting up in bed shortly after +morphine and eating a big tray of food with no nausea!
Except for one time when I tried to start on too high a dose of buprenorphine (I need to start at 1/2 mL and then increase to 1 mL), I've never gotten nausea from opioids. How much morphine were you on?
-elizabeth
poster:Elizabeth
thread:82248
URL: http://www.dr-bob.org/babble/20011025/msgs/82890.html