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Re: Trazodone vs. nefazodon

Posted by Noa on October 29, 2001, at 17:34:02

In reply to Trazodone vs. nefazodon, posted by martin741 on October 28, 2001, at 11:23:50

My personal experience: Trazodone was immediately and intensely sedating, while Nefazodone has a longer acting and less intense sedative effect on me.

I was not on a therapeutic dose of Trazodone, just enough to go to sleep (ie, counter the insomnia of serotonergic meds such as paxil and effexor). When I had some effexor poop-out/intolerance of higher doses, my pdoc suggested plugging in the nefazodone both for the sleep and for the antidepressant effect/augmentation.

Over time, my ratio of effexor:nefazodone has flipped. I started at 375 effexor:200 nefazodone, and gradually moved to where I am now, which is 262.5 effexor:500 nefazodone.

It is sedating for me in the hours after taking it but it doesn't cause sedation for me throughout the 24 hour cycle. I take it all a couple of hours before bed.


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