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Re: Cal Rocket Fuel - Clarification on modaf study

Posted by houstongirl on October 29, 2001, at 13:42:13

In reply to Re: Cal Rocket Fuel - Clarification on modaf study » SLS, posted by Rick on October 29, 2001, at 1:36:25

I thought there was a known metabolic interaction between citalopram and modafinil?

> >I don't know if it is relevant, but the majority of patients who responded in the small open-label study of modafinil-augmentation often cited were taking bupropion. I think this was more the result of patient selection than rate of response.
>
>
> - Scott
>
> >Clin Psychiatry 2000 May;61(5):378-81 Related Articles, Books
>
>
> >Modafinil augmentation of antidepressant treatment in depression.
>
> >Menza MA, Kaufman KR, Castellanos A.
>
>
> This may be even *less* relevant, but for the record there were 7 patients in the Provigil (modafinil) augmentation study often cited. Here's the lineup:
> #1 Celexa (citalopram) and Wellbutrin (bupropion)
> #2 Wellbutrin and Deseryl (trazodone)
> #3 Celexa
> #4 Celexa
> #5 Wellbutrin, Depakote (divalproex), and Lamictal (limotrigine)
> #6 Serzone (nefazodone) and Paxil (paroxetine)
> #7 Effexor (venlafaxine)
>
> The attached link gives more patient details including age, diagnosis, previous meds, time to initial effect, and brief analysis.
>
> Rick
>
> http://alertpubs.com/august2000psych.htm#Stimulant Augmentation in Depression


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poster:houstongirl thread:81334
URL: http://www.dr-bob.org/babble/20011025/msgs/82577.html