Posted by Elizabeth on October 19, 2001, at 12:28:24
In reply to Re: California Rocket Fuel+++ » Elizabeth, posted by SLS on October 16, 2001, at 19:14:51
> No. I'm pretty sure modafinil doesn't inhibit at all the reuptake of dopamine at therapeutic dosages, and binds with low affinity to the DA transporter.
I'll look it up at some point. I don't have access to my books right now.
> In the days before the flood, pemoline was considered to promote the passive release of dopamine presynaptically. It did not promote vesicular release.
Well, Abbott, at any rate, denies knowledge of what it does. :-)
> I don't know if it is relevant, but the majority of patients who responded in the small open-label study of modafinil-augmentation often cited were taking bupropion.
That's interesting, since bupropion is one of the ingredients in "CRF+++."
> I think this was more the result of patient selection than rate of response.
Maybe.
-elizabeth
poster:Elizabeth
thread:81334
URL: http://www.dr-bob.org/babble/20011015/msgs/81676.html