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Re: Stimulants take how long to work? Adamie

Posted by JohnL on August 17, 2001, at 18:45:30

In reply to Re: Stimulants take how long to work? Adamie » JohnL, posted by adamie on August 16, 2001, at 15:42:58


> hi john. the 5mg was extremely sedating 2 hours after taking. it was 7pm when i took it last night. and the sedation lasted until 3pm today. But it should go down. the sedation. I need the zyprexa as an AD. The pdoc before said we could raise it to 10mg... would 5mg be enough for good anti depressant effect?
>
> perhaps taking it with wellbutrin would be good. and a stimulant along with them.

Hi Adamie,
There isn't any concrete dosage of Zyprexa that I am aware for depression. But just based on my own anecdotal observations I think the doses are in the 2.5mg to 10mg range. I take 5mg. But I also must admit that as much as I like Zyprexa, I am not so sure about its ability to be a stand alone antidepressant. I think it instead is a wonderful companion to turbocharge an antidepressant. For some strange reason it seems to go especially well with Prozac, and there have been clinical studies done in that area that look very interesting and promising. My favorite all star combo though involves an antidepressant (preferably Prozac), Zyprexa (sometimes Risperdal instead), and a stimulant (Adrafinil is especially special with Prozac and/or Zyprexa).

The sedation you are experiencing will diminish, so don't let that discourage you. If it is just too much, then take a sharp knife and cut the pill in half to make 2.5mg. Get used to that first before going back to 5mg. Don't worry if you can't cut the pieces exactly, they don't have to be real accurate. But just cut them one at a time as needed. Don't cut a bunch in advance, as the inside can degrade once exposed to air. In the meantime, consider starting 2.5mg to 10mg Prozac (mix the contents of a capsule in orange juice and drink custom size doses, saving the rest in the fridge for next time, stir well each time), and order some Adrafinil. If I sound overly confident about this combination, it is because I am indeed very confident about it. Mileage does vary of course, but I have to admit that if we view this whole thing as a hit and miss game, the odds are dramatically in your favor with such a combo.
John


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