Posted by adamie on August 15, 2001, at 16:43:25
In reply to Re: why Zyprexa ?, posted by ben on August 15, 2001, at 16:14:02
> Why do yo take Zyprexa ....or depression? Alone or i combo with other meds ? Zyprexa primary for psychosis like schizophrenia and it has some antidepressant properities. I tried it too but only 2.5 mg at night knocked me out...too much sedation ! I had the expierence that antipsychotics like Zyprexa or Fluanxol (Flupentixol) made me indifferent...I didnt like this feeling.
hi. I made zyprexa my choice instead of another AD because perhaps AD's just dont work well for me. But I guess it could be just ssri's. Regardless I have read some good things about zyprexa. How it's supossed to be good for restoring emotions. Sedation I dont like because the depression makes me sleep well enough (naturally I would have an active mind and therefor natural insomnia) but I'm will to accept that if the Zyprexa can work very well. The only thing that matters is for me to feel better. Zyprexa works for dopamine and norepinephrine. So instead of trying wellbutrin I chose this for the fact that zyprexa can cause weight gain as apossed to wellbutrin which can cause quite a bit of weight loss. If it weren't for that then maybe I would have picked wellbutrin. I certainly need stimulation. Due to my depression I sometimes lose a lot of weight so I really could go anorexic with wellbutrin. Trying another class than AD's could be the thing for me. I certainly hope to see my condition not made worse by zyprexa in the coming days. Because that is exactly what those two seratonin meds did. If zyprexa doesn't make me worse then perhaps it has a great chance of making me much better in some weeks. I will try my first dose in a few hours. I am started at 5mg and the doctors at the hospital said if I tolerate it well they will increase the dose to 10mg for friday. I have tolerated paxil and effexor well so no exception should be seen here. but perhaps side effects would be a good indication the zyprexa could work.
I did have only very few side effects from effexor. Effexor the first dose I took made me feel detached from the world and everything was dark. It was quite scary. Aside from that which was generally a worsening of depression it gave me mild ringing in my left ear. this only happened one day for very little time. no other side effects except effects from worsening depression which has been severe drop in appetite, feeling extra horrible, suicidal (considering ECT as soon as possible it made me feel), and other such symptoms.
the paxil just made me numb and made me feel bad overall. stopping made my mood much better. I was really amazed. such a huge improvement. it's strange how these meds have been for me.
so I will see how this Zyprexa goes. Perhaps side effects would be good. indicating it could make me better.
>I know that there are people having great success with Zyprexa but everyone reacts as an individual. I would rather try other AD... perhaps an old tricyclic compund which acts on noradrenaline (because of your bad reaction on ssris) like desipramine or nortryptiline.
Despite me not wanting to try other AD's Despiramine I seen on an informative website acts slightly for seratonin also. Perhaps this is not true but I dont want to take any chances. And AD's in general I am not considering for now due to the previous bad experience.
>Reboxetine (Edronax / Vestra) could be an option too. Tried it with limited success....very good on cognitive function (concentration) and energy (for me like a real stimulant)....but the effect on mood pooped out very quickly.
this is exactly why I wanted to try reboxetine. but the pdoc earlier told me how it can be very sedating and just not effective in general. and she convinced me to try effexor. oh well. I exactly need much improved concentration. reboxetine would have been a choice. but for now I dunno what would be next for me if zyprexa fails or i cannot get stimulants. but no no. zyprexa must must work. me hopes it does.
> Dont give up ! I go through the same anoying and fustrating process of trying and trying meds......I am sure you will find one or a combo which works for you....perhaps it is Zyprexa, no one knows it in prieview !
> Good luck !thanks for the reply. take care.
> > thanks for the info. I hope to get one of these stimulants as soon as I can. I just got zyprexa and if it doesn't have the worsening effect of those seratonin meds then I hope to really stick with it and augment with a stimulant. stimulants may just be temporary relief but that is exactly what I need. temporary relief for 1 year because then my accutane depression should all be gone. it's a depression caused by a medication that goes away over time. so I just need temporary relief now. thanks for the reply.
> >
> > > Stimulants like Methylphenidate (Ritalin) or Amphetamines (Dexedrine) are used for antidepressant augmentation. They dont really have antidepressant action but noth can give you energy to do your stuff instead of sitting around an ruminating....and that could be worth a lot. Many docs are afraid of prescribing them because of addiction. In fact it is seldom that persons suffer from a single depression abuse them. It is more common for people suffering from a personality disorder or polytoxicomaniacs..... I think a good respect of this drugs is needed to use them. I tried Ritalin for my strong sedation of Paxil. My experience is mixed. First I tried 2.5 mg in form of the normal tablet. I quickly felt dizziness for a while...then I had a boost of energy and mood...and 4 hours later I crashed (exhaustion, more depressed feelings). Then I tried the slow release tablet (Ritalin SR) and I didnt felt such dizziness....it made me relaxed and more focused. My doc said that you have to try it several days in different dosage. I am still trying (since two weeks) and found 10 mg two to three times daily the best result. I dondt take it every day. The problem with Ritalin is the short half life (2 h) so you have to take it usually 3 (or more) times daily....if not it is possible that you experience ups and dows (energy and mood). To avoid this you can try Amphetamine (Dexedrin) which works longer (half life 7h). it is possible that one works really better for you than the other one...so try perhaps both. Adrafinil and Provigil are options too but there is not such a long experience with this two drugs...newer doesnt mean better....but you could try them too. And they work totally different . I dondt know if (and how) they affect mood.
> > > Good luck
> > > > Stimulants work right away -- you'll know within an hour or two how it works for you. I have found that Ritilan causes me rebound depression -- when the effect of it wears off (in about 3 or 4 hours) my depression is worse. Taking more just makes things worse -- each time I took it, it worked less and made me more depressed.
> > > >
> > > > Adderall does not have that same effect on me because it is longer acting. It helps my concentration and gives me energy. It also kicks in right away, and lasts about 6 hours or so. I am not taking it alone, however -- I am also taking Prozac, and will be adding Buspar to help with agitation. I'm not convinced that Adderall alone could help my depression.
> > > >
> > > > Wellbutrin is a good option to try, as someone else mentioned ... it is an antidepressant but not an SSRI, and it is more stimulating that many of the SSRIs. Effexor was horrible for me too, by the way.
> > > >
> > > > Good luck! I know how hard it is to keep searching for the right thing. I've been searching for a long time now, but I keep getting closer to the right "mix" for me.
> > > >
> > > > Take care,
> > > > cindy
> > > >
> > > > >
> > > > > hi everyone. Before persueing such things as VNS for depression I am willing to try stimulants if I am able to get them from my stubborn pdoc.
> > > > >
> > > > > Stimulants such as Ritalin and Adderall are supossed to be fast acting for depression correct? As in even in a few days? Maybe less? I have tried two seratonin medications and there is no doubt in my mind that they made me worse. While on effexor thoughts of hopelessness and possible suicide were extremely high. My heart was beating so fast that I actually had some heart pain. Off the effexor I am feeling better.
> > > > >
> > > > > Due to my bad experience with AD's so far I really want to try stimulants as a few people have suggested. Which are the best stimulants that could be easy to get for depression? If my pdoc wont prescribe me then I will try to get one from my family physician. So far I am thinking Ritalin and Adderall but I dont know if there are better ones for depression.
poster:adamie
thread:75133
URL: http://www.dr-bob.org/babble/20010814/msgs/75174.html