Posted by Elizabeth on July 19, 2001, at 12:18:42
In reply to Re: Thorazine and brain damage, posted by Else on July 18, 2001, at 18:56:26
> Wouldn't dopamine blockade cause further sedation?
It's not exactly sedation. I've taken antipsychotic drugs (Moban, droperidol) that weren't very sedating for me, but made me very passive in a way that's hard to describe. Then there have been others that didn't have much of the immobilising effect, but just made me feel tired and sleep a lot (Zyprexa, Mellaril). None of them did any good for me.
Seroquel for SSRI-associated apathy? That's interesting. If you do try it, please let me know what the outcome is. When I tried it, Seroquel didn't seem to do much of anything except make me tired. Unfortunately (since I was using it for insomnia), I kept having to increase the dose every few days to maintain the effect.
> I figured since drugs like amphetamines promote alertness by stimulating dopamine and noradrenaline release, then blocking these receptors would do the opposite (make you drowsy) regardless of antihistamine effect.
It's weirder than just being drowsy. It's a sensation that I've never experienced other than on certain antipsychotic drugs.
> I just saw my brother look like a vegetable on Risperdal and assumed it was sedation since he wasn't psychotic, just hysterical (in the vaguest sense of the word, he threw little tantrums and my parents wanted to make him more manageable).
And they gave him Risperdal for that? Did it help at all? I'd think more along the lines of a stimulant, an SSRI, Buspar, clonidine, lithium, or an anticonvulsant.
-elizabeth
poster:Elizabeth
thread:69927
URL: http://www.dr-bob.org/babble/20010714/msgs/70860.html