Posted by MB on July 18, 2001, at 21:14:49
In reply to Re: Thorazine and brain damage » MB, posted by Elizabeth on July 18, 2001, at 20:26:49
> > I wish there was a way to block the antihistaminic action of these psychotropic drugs.
>
> Some are more antihistaminic than others. Haldol, Stelazine, and Moban are some of the less sedating antipsychotics. Desipramine is the least antihistaminic of the tricyclic antidepressants (although protriptyline is probably more activating).Hey Elizabeth,
I'll have to remember that (above list of less sedating meds). Here are the antihistaminic drugs I've tried: amitryptaline, nortryptaline, olanzapine, thorazine (in my aforementioned act of recreational stupidity < g >), and Remeron. How do those compare to the drugs you mentioned above in terms of antihistaminic action? I have a feeling I'll need to see a pdoc soon for medication (as much as I hate meds, it's been six months off of them, and I've held on as long as I think I can), and might consider the drugs you mentioned (that is, if the doc insists on a tricyclic or neuroleptic).
> > Remeron would have been perfect for me if it hadn't have been for the antihistamine sedation.
>
> How much Remeron were you on.I started at 15mg and moved up to 30mg. Probably not enough for the noradrenergic effect to cancel the antihistamine effect, but I was so zombified from the 30mg that I was scared to go any higher. Also, I was too fatigued to make the twice daily trips to the grocery store necessary to keep my kitchen stocked with food < g >.
> > I guess an H-1 agonist (to counteract the H-1 blocking action of these drugs) would make a person miserable. Wouldn't it cause allergic-type reactions?
>
> Yes, that's one thing histamine does. Opioids, for example, cause histamine release (to varying degrees) which is why a lot of people get itchy on them. Promethazine, diphenhydramine, doxepin, and other antihistamines can be used to prevent the itching."Got so high, I scratched 'til I bled...," Kurt Cobain.
> > parenthetically, can you believe my doctor switched me to Remeron when I told him Paxil was making me too tired and that I was gaining weight? Do these guys even listen?
>
> I take it your question is a rhetorical one. < g >Yeah, just whining as usual...
poster:MB
thread:69927
URL: http://www.dr-bob.org/babble/20010714/msgs/70739.html